Position held

Honorary Consultant in Neuroanaesthesia and Neurocritical Care at the National Hospital for Neurology and Neurosurgery, University College London Hospitals, and Honorary Professor at University College London.

Why does the nominee deserve the award?

Professor Smith should be awarded the first NACCS Lifetime Achievement Award as he has devoted his career to the practice, research and teaching of Neuroanaesthesia and Neurocritical Care along with his extensive commitment to the Neuroanaesthesia and Critical Care Society.

Achievements Include:

• Editor-in-Chief, the Journal of Neurosurgical Anesthesiology (current)
• Past President of the Society for Neuroscience in Anesthesiology and Critical Care
• Past President of the Neuroanaesthesia and Critical Care Society of Great Britain and Ireland
• Past President of the Critical Care Medicine Section, Royal Society of Medicine
• Examiner for the Fellowship of the Faculty on Intensive Care Medicine
• External Examiner of the MSc in Anaesthesia and Perioperative Medicine, Brighton and Sussex Medical School
• Chair of the independent Data Monitoring and Ethics Committees of two NIHR-funded clinical trials: (i) Randomised Evaluation of Surgery with Craniectomy for patients Undergoing Evacuation of Acute SubDural Haematoma (RESCUE-ASDH) (ii) Randomised, double blind, placebo-controlled trial of a two week course of Dexamethasone for adult patients with a symptomatic Chronic SubDural Haematoma (Dex-CSDH)

Support from the NHNN Anaesthetic and Critical Care Department:

Professor Smith has spent his career, both as a Neuroanaesthetist and Neurocritical Care consultant, supporting and encouraging staff in all healthcare professions and at all levels of training. Through developing staff he has built a successful specialist Neurosurgical Critical Care unit, and has inspired many who have worked with him to take up a career in the Neurosciences. He has fostered strong links with both UCL and international organisations through his research interests, which continue to exist today after his retirement from clinical work, and despite now being retired continues to support the critical care, and Neuroanaesthetic departments in both educational and research interests.

He has the full support of the department in his nomination for the award.

Research Overview:

Professor Smith is clinical lead of a multidisciplinary research collaboration of clinical scientists at UCLH and medical physicists and biomedical engineers in the Department of Medical Physics and Bioengineering , UCL. The group is internationally recognised for its work in the development and clinical translation of optical devices for the continuous monitoring of cerebral haemodynamics, oxygenation and metabolism. Over the last 15 years this group has been supported by research grants (> £2.2 millions) from the Medical Research Council, Wellcome Trust, Engineering and Physical Sciences Research Council, National institute for Academic Anaesthesia, UCLH/UCL Biomedical Research Centre, and the Central and East London CLRN.

Publications:

Professor Smith has contributed to over 283 publications spanning over a 30 year period.

Selected recent publications:

Smith M. Multimodality neuromonitoring in adult traumatic brain injury: a narrative review. Anesthesiology 2018: 128: 401-15

Smith M. Refractory intracranial hypertension: the role of decompressive craniectomy. Anesth Analg 2017; 125: 1999-2008

Ghosh A, Highton D, Kolyva C, Tachtsidis I, Elwell C, Smith M. Hyperoxia results in increased aerobic metabolism following acute brain injury. J Cereb Blood Flow Metab  2017; 37: 2910-2

Smith M, Citerio G. Death determined by neurological criteria: the next steps. Intensive Care Med  2017: 43: 1383-5

Brigadoi S, Phan P, Highton D, Powell S, Cooper R, Hebden J, Smith M, Tachtsidis I, Elwell C, Gibson A. Image reconstruction of oxidized cerebral cytochrome C oxidase changes from broadband near-infrared spectroscopy data. Neurophotonics  2017; 4: 021105

Phan P, Highton D,­ Lai J, Smith M, Elwell C, Tachtsidis I. Multi-channel multi-distance broadband near-infrared spectroscopy system to measure the spatial response of cellular oxygen metabolism and tissue oxygenation. Biomed Opt Express  2016; 7: 4424-40

Grieve R, Sadique Z, Gomes M, Smith M, Lecky F, Hutchinson P, Menon D, Rowan K, Harrison D and on behalf of the Risk Adjustment in Neurocritical Care (RAIN) Study Investigators. An evaluation of the clinical and cost-effectiveness of alternative care locations for critically ill adult patients with acute traumatic brain injury. Br J Neurosurg  2016; 30: 388-96

Kirkman M, Smith M. Challenges in the anesthetic and intensive care management of acute ischemic stroke. J Nurosurg Anesthesiol  2016; 28: 214-232

Citerio G, Cypel M, Dobb GJ, Dominguez-Gil B, Frontera JA, Greer DM, Manara AR, Shemie SD, Smith M, Valenza F, Wijdicks EF. Organ donation in adults: a critical care perspective. Intensive Care Med 2016; 42: 305-15

Highton D, Ghosh A, Tachtsidis I, Panovska-Griffiths J, Elwell CE, Smith M. Monitoring Cerebral Autoregulation after brain injury: multimodal assessment of cerebral slow-Wave oscillations using near-infrared spectroscopy. Anesth Analg 2015; 121: 198-205

Caldwell M, Hapuarachchi T, Highton D, Elwell C, Smith M, Tachtsidis I. BrainSignals revisited: simplifying a computational model of cerebral physiology. PLOS ONE 2015; 10: e0126695

Wijdicks E, Menon D, Smith M. The things you need to know to practice neurologic critical care. Intensive Care Med 2015: 41: 318-21

Smith M, Citerio G. What’s new in subarachnoid haemorrhage. Intensive Care Med 2015; 41: 123-6

Kolyva C, Ghosh A, Tachtsidis I, Highton D, Cooper C, Smith M, Elwell C. Cytochrome c oxidase response to changes in cerebral oxygen delivery in the adult shows higher brain-specificity than haemoglobin. Neuroimage 2014: 85: 234-44

Kirkman M, Citerio G, Smith M. The intensive care management of acute ischaemic stroke: an overview. Intensive Care Medicine 2014: 40: 640-53

Kirkman M, Smith M. Intracranial pressure monitoring, cerebral perfusion pressure estimation, and ICP-CPP guided therapy: a standard of care or an optional extra after brain injury? Brit J Anaesth 2013; 112: 35-36